Procollagen III
Biomarker1 paper1 finding
- Human trial1
Interventions
1Tirzepatide
downin humans1Moderate certainty
1 study
Tirzepatide
downin humans1Moderate certainty
Tirzepatide decreases procollagen III in humans (-21.3% and -24.8% vs -3.8%).
Human trialobesity disease without diabetesweek 72n = 225
Changes in Abdominal Adiposity and Associations With Metabolic Health Markers Following Tirzepatide in Japanese Participants With Obesity Disease: Results From the SURMOUNT-J Study · Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 19 Sep 2026