Prefrontal cortex oxygenation

1. Dual-task testing increases prefrontal cortex oxygenation in humans.

   “Within the SCD group, ∆HbO2 was greater during the dual compared to single cognitive condition (p = .002) and between the SCD and non-SCD groups (p = .016).”

   Human trialduring dual-task compared to single tasks

   Investigating dual-task biomarkers of subjective cognitive decline using functional near-infrared spectroscopy

   Neurobiology of aging·7 Jan 2026

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1. Moderate-to-vigorous physical activity increases prefrontal cortex oxygenation in humans (r = 0.39, P = 0.02).

   “positively correlated to the ΔO2Hb responses (r = 0.39. P = 0.02) during the executive task.”

   Humansprefrontal cortex

   Greater habitual moderate-to-vigorous physical activity is associated with better executive function and higher prefrontal oxygenation in older adults

   GeroScience·3 Jun 2021

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