Polygenic score for hand grip strength

Biomarker

1 paper studies it1 more mentions it4 findings

  • Humans1

Effects

2

Survival

no changein humans1

1 study
  1. Polygenic score for hand grip strength has no effect on survival in humans.

    “PGS HGS was not associated with better survival after acute adverse health events compared to the nondiseased period.”

    Humansafter acute adverse health eventsn = 342,443

    Genome-Wide Polygenic Score for Muscle Strength Predicts Risk for Common Diseases and Lifespan: A Prospective Cohort Study

    The journals of gerontology. Series A, Biological sciences and medical sciences

Body mass index

downin humans1

1 study
  1. Polygenic score for hand grip strength decreases body mass index in humans (β = -0.112 kg/m2, SE = 0.017, p = 1.69E-11).

    “A 1 standard deviation (SD) increase in the PGS HGS predicted a lower body mass index (β = -0.112 kg/m2, standard error [SE] = 0.017, p = 1.69E-11) in women”

    Humansfemalesn = 342,443

    Genome-Wide Polygenic Score for Muscle Strength Predicts Risk for Common Diseases and Lifespan: A Prospective Cohort Study

    The journals of gerontology. Series A, Biological sciences and medical sciences

Associations

2

Noncommunicable disease

downin humans1

1 study
  1. Polygenic score for hand grip strength lowers the risk of noncommunicable disease in humans (reduced risk by 2%-10%).

    “A higher PGS HGS was associated with a reduced risk of selected common noncommunicable diseases and mortality by 2%-10%.”

    Humansn = 342,443

    Genome-Wide Polygenic Score for Muscle Strength Predicts Risk for Common Diseases and Lifespan: A Prospective Cohort Study

    The journals of gerontology. Series A, Biological sciences and medical sciences

More on Noncommunicable disease

Mortality

downin humans1

1 study
  1. Polygenic score for hand grip strength lowers the risk of mortality in humans (reduced risk by 2%-10%).

    “A higher PGS HGS was associated with a reduced risk of selected common noncommunicable diseases and mortality by 2%-10%.”

    Humansn = 342,443

    Genome-Wide Polygenic Score for Muscle Strength Predicts Risk for Common Diseases and Lifespan: A Prospective Cohort Study

    The journals of gerontology. Series A, Biological sciences and medical sciences

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