Polygenic risk score for hand grip strength

Biomarker

1 paper4 findings

  • Humans1

Associations

4

Disability

downin humans1

1 study
  1. Polygenic risk score for hand grip strength lowers the risk of disability in humans (odds ratio = 0.74-0.76).

    “participants with higher PRS HGS were less likely to have ADL/IADL disabilities (odds ratio = 0.74-0.76).”

    Humansfemalesn = 429

    A Polygenic Risk Score for Hand Grip Strength Predicts Muscle Strength and Proximal and Distal Functional Outcomes among Older Women

    Medicine and science in sports and exerciseJun 30, 2022

Ankle plantarflexion strength

upin humans1

1 study
  1. Polygenic risk score for hand grip strength predicts ankle plantarflexion strength in humans (1.2% of variation, β = 9.4, SE = 4.2, P = 0.027).

    “1.2% of the variation in ankle plantarflexion strength ( β = 9.4, SE = 4.2, P = 0.027)”

    Humansfemalesn = 429

    A Polygenic Risk Score for Hand Grip Strength Predicts Muscle Strength and Proximal and Distal Functional Outcomes among Older Women

    Medicine and science in sports and exerciseJun 30, 2022

Isometric knee-extension strength

upin humans1

1 study
  1. Polygenic risk score for hand grip strength predicts isometric knee-extension strength in humans (5.4% of variation, β = 19.6, SE = 4.7, P < 0.001).

    “5.4% of the variation in knee extension strength ( β = 19.6, SE = 4.7, P < 0.001)”

    Humansfemalesn = 429

    A Polygenic Risk Score for Hand Grip Strength Predicts Muscle Strength and Proximal and Distal Functional Outcomes among Older Women

    Medicine and science in sports and exerciseJun 30, 2022

Hand grip strength

upin humans1

1 study
  1. Polygenic risk score for hand grip strength predicts hand grip strength in humans (β = 4.8, SE = 0.93, P < 0.001).

    “The measured HGS increased linearly over increasing PRS ( β = 4.8, SE = 0.93, P < 0.001).”

    Humansfemalesn = 429

    A Polygenic Risk Score for Hand Grip Strength Predicts Muscle Strength and Proximal and Distal Functional Outcomes among Older Women

    Medicine and science in sports and exerciseJun 30, 2022

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