Polygenic risk score for blood pressure

1. Polygenic risk score for blood pressure is associated with diastolic blood pressure in humans (0.24 (95% CI, 0.02-0.45) mm Hg/y).

   Humanshighest vs lowest quartile in postpuberty3.00 yearsn = 2,549

   Effects of Polygenic Risk Scores and Physical Activity on Blood Pressure Trajectories in Childhood, Adolescence, and Young Adulthood · Circulation. Genomic and precision medicine · 24 Sep 2026

Diastolic blood pressure →

1. Polygenic risk score for blood pressure is associated with systolic blood pressure in humans (1.70, 1.65, and 2.92 mm Hg).

   Humansper 1 SD PRS

   Effects of Polygenic Risk Scores and Physical Activity on Blood Pressure Trajectories in Childhood, Adolescence, and Young Adulthood · Circulation. Genomic and precision medicine · 24 Sep 2026

Systolic blood pressure →