Phosphodiesters

1 paper1 finding

Humans1

Upstream

1

Age

upin humans1

1 study

Age increases phosphodiesters in humans.
“whereas PDEs showed the opposite age difference.”
Humansbrain
Mapping Age Differences in Brain Energy Metabolites and Metabolic Markers of Cellular Membrane Production and Degradation With ³¹P Magnetic Resonance Spectroscopy
Human brain mappingOct 1, 2024

Latest

Human Brain MappingOct 11

Mapping Age Differences in Brain Energy Metabolites and Metabolic Markers of Cellular Membrane Production and Degradation With ³¹P Magnetic Resonance Spectroscopy

Cross-sectional study of 80 peopleOxidative phosphorylation

Journal of Magnetic Resonance ImagingApr 9

Multiparametric Aging Study Across Adulthood in the Leg Through Quantitative MR Imaging, ¹H Spectroscopy, and ³¹P Spectroscopy at 3T

Cohort study of 70 peopleBiomarkers

PLOS GeneticsSep 21

Neuronal expression in Drosophila of an evolutionarily conserved metallophosphodiesterase reveals pleiotropic roles in longevity and odorant response

Experiments in fliesImmune response

Frontiers in Aging NeuroscienceJun 5

Systematic review of ³¹P-magnetic resonance spectroscopy studies of brain high energy phosphates and membrane phospholipids in aging and Alzheimer's disease

ReviewBiomarkers

Aging CellMay 30

Older adults with sarcopenia have distinct skeletal muscle phosphodiester, phosphocreatine, and phospholipid profiles

Study in peopleMechanisms

bioRxivMay 10

An evolutionarily conserved metallophosphodiesterase is a determinant of lifespan in Drosophila

Preprint: experiments in model organismsMechanisms

PreprintSep 18

Accelerating the human aging clock by mutating an epigenetic gene

Preprint: reviewBiomarkers