PH-fibrosis%

1. PH-fibrosis% is associated with interstitial lung abnormalities in the LCS and Kyoto University cohorts.

   “Higher PH-fibrosis% was associated with interstitial lung abnormalities in the LCS and Kyoto University cohorts.”

   Humansin the LCS and Kyoto University cohorts

   Lung scarring linked to flare-ups in chronic lung disease

   The European respiratory journal·Feb 27, 2026

More on Interstitial lung abnormalities

1. PH-fibrosis% is associated with mortality in humans (Kyoto University cohort) (HR 1.94).

   “In the Kyoto University cohort, higher PH-fibrosis% was significantly associated with increased mortality (HR 1.94), with a similar trend in the Kyoto-Himeji cohort (HR 1.86).”

   HumansKyoto University cohort

   Lung scarring linked to flare-ups in chronic lung disease

   The European respiratory journal·Feb 27, 2026

1. PH-fibrosis% is linked with a higher risk of COPD exacerbation in humans (independent of emphysema and airway wall thickness) (HR 1.39).

   “significant associations between higher baseline PH-fibrosis% and future exacerbation risk independent of emphysema and airway wall thickness (hazard ratio (HR) 1.39 and 3.35 for Kyoto University and Kyoto-Himeji, respectively)”

   Humansindependent of emphysema and airway wall thickness

   Lung scarring linked to flare-ups in chronic lung disease

   The European respiratory journal·Feb 27, 2026