Pause-to-word ratio

Amyloid-beta pathology is associated with pause-to-word ratio in humans (beta=0.05, p = 0.040).

“trends towards a higher pause‐to‐word ratio (picture description: beta=0.05, p = 0.040; journaling: beta=0.07, p = 0.032) and higher pronoun‐to‐noun ratio (picture description: beta=0.03, p = 0.033) in Aβ‐positive individuals.”

Humanspicture description task

Longitudinal at‐home assessment of connected speech acoustics in Dutch amyloid‐positive cognitively normal adults

AAIC 2025 abstract·24 Dec 2025