PAR

1. PAR is associated with cancer prevalence in humans (Chinese hospital cohort).

   “In the hospital cohort, MLR, NMLR, SIRI, SII, NLR, PLR, CAR, CLR, PIV, IBI, NPAR, and PAR were positively associated with cancer prevalence”

   HumansChinese hospital cohortperipheral blood

   Association between fifteen peripheral blood inflammatory markers and cancer prevalence: A cross-sectional study based on NHANES and a Chinese hospital cohort

   Frontiers in oncology·Oct 30, 2026

More on Cancer prevalence

1. Emphysema is associated with PAR in humans (10-year higher PARS).

   “Participants with a history of asthma and emphysema had 4- and 10-year higher PARS.”

   Humans

   Physiological Aging of the Respiratory System (PARS): from development to application

   medRxiv·Jun 16, 2026Preprint

More on Emphysema

1. Asthma is associated with PAR in humans (4-year higher PARS).

   “Participants with a history of asthma and emphysema had 4- and 10-year higher PARS.”

   Humans

   Physiological Aging of the Respiratory System (PARS): from development to application

   medRxiv·Jun 16, 2026Preprint

More on Asthma

1. Cigarette smoking is associated with PAR in humans.

   “Cigarette smoking, lower socioeconomic status, black race, higher serum cadmium, and lower serum selenium and magnesium were associated with higher PARS.”

   Humans

   Physiological Aging of the Respiratory System (PARS): from development to application

   medRxiv·Jun 16, 2026Preprint

More on Cigarette smoking

1. PAR is linked with a higher risk of mortality in humans (HR 1.06 per year (95%CI 1.05-1.07)).

   “PARS was associated with a higher mortality (HR = 1.06, 95%CI: 1.05-1.07 per year)”

   Humans116 months

   Physiological Aging of the Respiratory System (PARS): from development to application

   medRxiv·Jun 16, 2026Preprint