PAM activity
Biomarker1 paper1 finding
- Humans1
Effects
1Vascular dementia
no changein humans1
1 study
Vascular dementia
no changein humans1
PAM activity has no effect on vascular dementia in humans.
Humansmean follow-up of 4.75 ± 1.3 yearsn = 4,543
Reduced peptide amidation links to higher Alzheimer's risk · Alzheimer's research & therapy · 28 Sep 2026
Latest
1Alzheimer's Research & TherapyHumans
Reduced peptide amidation links to higher Alzheimer's risk
In 4,543 adults, each standard deviation drop in amidation enzyme activity raised incident Alzheimer's risk with an adjusted hazard ratio of 2.30.In 4,543 adults, each standard deviation drop in amidation enzyme activity raised incident Alzheimer's risk with an adjusted hazard ratio of 2.30.