Outer RPE layer thickness

Age is associated with outer RPE layer thickness in humans.

“For the outer hyperreflective RPE layer, an increase in thickness with age was noted in the outer (H = 8.63; P = 0.013)”

Humanshealthy participantsouter macular regionn = 110

Automated Segmentation of Retinal Pigment Epithelium Layers in High-Resolution OCT

Ophthalmology science·Aug 4, 2026