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medRxiv

Severe vitamin D deficiency is linked to higher mortality

The mortality hazard ratio was 2.03 for participants with under 5 nanograms per millilitre of vitamin D compared with those with at least 20.The mortality hazard ratio was 2.03 for participants with under 5 nanograms per millilitre of vitamin D compared with those with at least 20.

Preprint: cohort study of 412,020 peopleVitamin D deficiency
The Journals of Gerontology, Series B

US study finds lasting Black–White gaps in local conditions

An observational study linked local records to US participants from ages 12–20 to 33–42 across 1994–2018, finding persistent racial disparities.An observational study linked local records to US participants from ages 12–20 to 33–42 across 1994–2018, finding persistent racial disparities.

Cohort study in peopleAI & data
Frontiers in Pharmacology

Melissic acid reduces senescence in human stem cells via cAMP signaling

A screen of 800 natural compounds identified a phytochemical that activates autophagy and restores cell-cycle activity in models of cellular exhaustion.A screen of 800 natural compounds identified a phytochemical that activates autophagy and restores cell-cycle activity in models of cellular exhaustion.

Experiments in human cellsInterventions