Observed-domain childhood adversity index

1. Observed-domain childhood adversity index is associated with incident cardiovascular disease in humans (HR 1.07, 95% CI 1.03–1.10 per additional observed adverse domain).

   HumansComplete-case risk sets; descriptive pooling across non-equivalent cohort-specific measures, adjusted for age, sex, birth cohort, smoking, alcohol, and BMIper additional observed adverse domain

   Cohort-specific childhood adversity measures and incident cardiovascular disease across four ageing cohorts: analyses of childhood hunger, later-life psychosocial indicators, and life-course burden · BMC public health · 5 Oct 2026

Incident cardiovascular disease →