Myopia genetic risk score
Biomarker3 findings
Effects
2Vertical cup-to-disc ratio
upin humans1
1 study
Vertical cup-to-disc ratio
upin humans1
Myopia genetic risk score increases vertical cup-to-disc ratio in humans (beta 0.005, 95% CI 0.003–0.007).
Humansn = 34,825
A Comprehensive Assessment of the Shared Genetic Architecture between Myopia and Open-Angle Glaucoma · Ophthalmology science · 22 Jul 2026
Intraocular pressure
upin humans1
1 study
Intraocular pressure
upin humans1
Myopia genetic risk score increases intraocular pressure in humans (beta 0.04 mmHg, 95% CI 0.00–0.08).
Humansn = 34,825
A Comprehensive Assessment of the Shared Genetic Architecture between Myopia and Open-Angle Glaucoma · Ophthalmology science · 22 Jul 2026
Associations
1Open-angle glaucoma
upin humans1OR 1.18
1 study
Open-angle glaucoma
upin humans1OR 1.18
Myopia genetic risk score raises the risk of open-angle glaucoma in humans (OR 1.18, 95% CI 1.09–1.28).
Humansn = 34,825
A Comprehensive Assessment of the Shared Genetic Architecture between Myopia and Open-Angle Glaucoma · Ophthalmology science · 22 Jul 2026