Myopia genetic risk score

Biomarker3 findings

Effects

2

Vertical cup-to-disc ratio

upin humans1

1 study
  1. Myopia genetic risk score increases vertical cup-to-disc ratio in humans (beta 0.005, 95% CI 0.003–0.007).

    Humansn = 34,825

    A Comprehensive Assessment of the Shared Genetic Architecture between Myopia and Open-Angle Glaucoma · Ophthalmology science · 22 Jul 2026

Vertical cup-to-disc ratio →

Intraocular pressure

upin humans1

1 study
  1. Myopia genetic risk score increases intraocular pressure in humans (beta 0.04 mmHg, 95% CI 0.00–0.08).

    Humansn = 34,825

    A Comprehensive Assessment of the Shared Genetic Architecture between Myopia and Open-Angle Glaucoma · Ophthalmology science · 22 Jul 2026

Intraocular pressure →

Associations

1

Open-angle glaucoma

upin humans1OR 1.18

1 study
  1. Myopia genetic risk score raises the risk of open-angle glaucoma in humans (OR 1.18, 95% CI 1.09–1.28).

    Humansn = 34,825

    A Comprehensive Assessment of the Shared Genetic Architecture between Myopia and Open-Angle Glaucoma · Ophthalmology science · 22 Jul 2026

Open-angle glaucoma →