Multiomics latent factor

1. Multiomics latent factor predicts progression to Alzheimer's disease in humans.

   “This factor also significantly predicted time to event, with participants exhibiting higher scores progressing to AD more quickly”

   Humansaccounting for agen = 391

   Multiomics Patterns and Alzheimer’s Disease Risk

   AAIC 2025 abstract·23 Dec 2025

1. Multiomics latent factor is associated with PET amyloid in humans (Rho = 0.20).

   “one of the factors was correlated with PET Amyloid levels (Rho = 0.20, controlling for age and APOE ε4)”

   Humanscontrolling for age and APOE ε4n = 391

   Multiomics Patterns and Alzheimer’s Disease Risk

   AAIC 2025 abstract·23 Dec 2025

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