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MRSCRP

Biomarker

1 paper studies it3 findings

  • Humans1

Effects

1

Total memory score

mediatesin humans1

1 study

  1. MRSCRP mediates total memory score in humans (6.9%).

    “MRSCRP mediated 6.9% of the relationship between high school education and total memory score in a model adjusting for age, sex, and genetic ancestry (p < .05)”

    Humanshigh school education and total memory scoren = 3,298

    DNA Methylation at C-Reactive Protein-Associated CpG Sites May Mediate the Pathway Between Educational Attainment and Cognition

    The journals of gerontology. Series A, Biological sciences and medical sciencesJun 19, 2024

Associations

2

Cognitive function

downin humans1

1 study

  1. MRSCRP is associated with cognitive function in humans (-0.43 items per SD MRSCRP).

    “for each standard deviation increase in MRSCRP, total memory score and total cognitive score decreased, on average, by 0.28 words and 0.43 items, respectively (p < .001).”

    Humansn = 3,298

    DNA Methylation at C-Reactive Protein-Associated CpG Sites May Mediate the Pathway Between Educational Attainment and Cognition

    The journals of gerontology. Series A, Biological sciences and medical sciencesJun 19, 2024

lnCRP

upin humans1

1 study

  1. MRSCRP is associated with lnCRP in humans (0.38 unit increase in lnCRP per SD MRSCRP).

    “each standard deviation increase in MRSCRP was associated with a 0.38 unit increase in lnCRP (p = 4.02E-99).”

    Humansn = 3,298

    DNA Methylation at C-Reactive Protein-Associated CpG Sites May Mediate the Pathway Between Educational Attainment and Cognition

    The journals of gerontology. Series A, Biological sciences and medical sciencesJun 19, 2024

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