Monoamine oxidase B availability
1 paper2 findings
- Humans1
Associations
2White matter lesion volume
downin humans1
1 study
White matter lesion volume
downin humans1
Monoamine oxidase B availability is associated with white matter lesion volume in humans (r = -0.33, p = 0.021).
“increased MAO-B levels (indicative of astrocyte reactivity) were associated with higher DAT availability (r = 0.53, p < 0.001) and reduced white matter lesion volumes (r = -0.33, p = 0.021).”
Humanshealthy older adultsn = 55
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism11 Apr 2026
Dopamine transporter availability
upin humans1
1 study
Dopamine transporter availability
upin humans1
Monoamine oxidase B availability is associated with dopamine transporter availability in humans (r = 0.53, p < 0.001).
“increased MAO-B levels (indicative of astrocyte reactivity) were associated with higher DAT availability (r = 0.53, p < 0.001)”
Humanshealthy older adultsn = 55
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism11 Apr 2026
Latest
1 in 12 monthsJournal of Cerebral Blood Flow and Metabolism
The role of dopamine decline, astrocyte reactivity and cerebral small-vessel disease in cognitive aging
Cohort study of 55 peopleMechanisms