MIR-154 family deregulation

Age is associated with MIR-154 family deregulation in rhesus monkeys.

“The MIR-154 family, inside the imprinted, rejuvenation-associated Dlk1-Dio3 cluster, was particularly vulnerable.”

Animalsnon-brain organs and brain regionsmale and females

Aging Rhesus Macaque show tissue and sex-specific balance of drifting and coordinated miRNA programs

bioRxiv (Cold Spring Harbor Laboratory)·30 Apr 2026Preprint