MACE prediction C-index

1. 12-metabolite signature improves MACE prediction C-index in humans (absolute difference 0.052, P < 0.001).

   Humansin participants with type 2 diabetes and lung function impairment12 yearsn = 3,706

   Metabolomic profiling refines cardiovascular risk stratification beyond SCORE2-diabetes in patients with concurrent type 2 diabetes and pulmonary dysfunction · Frontiers in endocrinology · 26 Aug 2026

12-metabolite signature →