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Low PEF–low grip declining trajectory

Biomarker

1 paper5 findings

  • Humans1

Associations

5

Mortality

upin humans1OR 3.49

1 study

  1. Low PEF–low grip declining trajectory is associated with mortality in humans (Adjusted OR 3.49, 95% CI 1.71–7.11).

    “mortality (OR, 3.49; 95% CI, 1.71–7.11)”

    HumansCompared with the very high PEF–very high grip trajectory2015–2018n = 11,630

    Low airflow and grip strength linked to disability and death

    Research Square14 Oct 2026Preprint

Frailty

upin humans1OR 2.29

1 study

  1. Low PEF–low grip declining trajectory is associated with frailty in humans (Adjusted OR 2.29, 95% CI 1.49–3.52).

    “frailty (OR, 2.29; 95% CI, 1.49–3.52)”

    HumansCompared with the very high PEF–very high grip trajectory2018 outcome assessmentn = 11,630

    Low airflow and grip strength linked to disability and death

    Research Square14 Oct 2026Preprint

Incident any ADL/IADL disability

upin humans1OR 1.85

1 study

  1. Low PEF–low grip declining trajectory is associated with incident any ADL/IADL disability in humans (Adjusted OR 1.85, 95% CI 1.25–2.74).

    “any ADL/IADL disability (OR, 1.85; 95% CI, 1.25–2.74)”

    HumansCompared with the very high PEF–very high grip trajectory2018 outcome assessmentn = 11,630

    Low airflow and grip strength linked to disability and death

    Research Square14 Oct 2026Preprint

Incident IADL disability

upin humans1OR 1.86

1 study

  1. Low PEF–low grip declining trajectory is associated with incident IADL disability in humans (Adjusted OR 1.86, 95% CI 1.24–2.79).

    “IADL disability (OR, 1.86; 95% CI, 1.24–2.79)”

    HumansCompared with the very high PEF–very high grip trajectory2018 outcome assessmentn = 11,630

    Low airflow and grip strength linked to disability and death

    Research Square14 Oct 2026Preprint

Incident ADL disability

upin humans1OR 2.24

1 study

  1. Low PEF–low grip declining trajectory is associated with incident ADL disability in humans (Adjusted OR 2.24, 95% CI 1.44–3.50).

    “the low PEF–low grip declining group had higher adjusted odds of incident ADL disability (odds ratio [OR], 2.24; 95% confidence interval [CI], 1.44–3.50)”

    HumansCompared with the very high PEF–very high grip trajectory2018 outcome assessmentn = 11,630

    Low airflow and grip strength linked to disability and death

    Research Square14 Oct 2026Preprint

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Research Square

Low airflow and grip strength linked to disability and death

Adults with persistently low airflow and low, declining grip strength had 3.49 times the odds of death compared with those with very high readings.Adults with persistently low airflow and low, declining grip strength had 3.49 times the odds of death compared with those with very high readings.

Preprint: cohort study of Chinese adults aged 45 years or older, against very high PEF–very high grip groupPopulations

Limit: Early or undiagnosed disease may influence both functional trajectories and subsequent disability or death

Paper

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