Loss of heterozygosity frequency

1. Pseudomonas entomophila has no effect on loss of heterozygosity frequency in flies.

   “infection with the enteric pathogenic bacteria, Erwinia carotovora carotovora 15 but not Pseudomonas entomophila increases LOH frequency”

   Model organismsintestinal stem cells

   Molecular Underpinnings and Environmental Drivers of Spontaneous Loss of Heterozygosity in Drosophila Intestinal Stem Cells

   bioRxiv (Cold Spring Harbor Laboratory)·Jul 22, 2022Preprint

More on Pseudomonas entomophila

1. Erwinia carotovora carotovora 15 increases loss of heterozygosity frequency in flies.

   “infection with the enteric pathogenic bacteria, Erwinia carotovora carotovora 15 but not Pseudomonas entomophila increases LOH frequency”

   Model organismsintestinal stem cells

   Molecular Underpinnings and Environmental Drivers of Spontaneous Loss of Heterozygosity in Drosophila Intestinal Stem Cells

   bioRxiv (Cold Spring Harbor Laboratory)·Jul 22, 2022Preprint

More on Erwinia carotovora carotovora 15

1. DNA repair mediates loss of heterozygosity frequency in flies.

   “Using whole-genome sequencing of somatic LOH events, we demonstrate that they arise primarily via mitotic recombination.”

   Model organismsintestinal stem cells

   Molecular Underpinnings and Environmental Drivers of Spontaneous Loss of Heterozygosity in Drosophila Intestinal Stem Cells

   bioRxiv (Cold Spring Harbor Laboratory)·Jul 22, 2022Preprint

More on DNA repair