Longitudinal proteomic aging index

Biomarker

1 paper5 findings

  • Humans1

Associations

5

Frailty

upin humans1

1 study
  1. Longitudinal proteomic aging index predicts frailty in humans.

    “higher LPAI was associated with increased multimorbidity and frailty.”

    Humans

    A Novel Longitudinal Proteomic Aging Index Predicts Mortality, Multimorbidity, and Frailty in Older Adults

    Aging cell8 Dec 2025

Multimorbidity

upin humans1

1 study
  1. Longitudinal proteomic aging index predicts multimorbidity in humans.

    “higher LPAI was associated with increased multimorbidity and frailty.”

    Humans

    A Novel Longitudinal Proteomic Aging Index Predicts Mortality, Multimorbidity, and Frailty in Older Adults

    Aging cell8 Dec 2025

Cancer mortality

upin humans1HR 1.96

1 study
  1. Longitudinal proteomic aging index predicts cancer mortality in humans (HR = 1.96, 95% CI: [1.45, 2.64] per SD).

    “cancer mortality (HR = 1.96, 95% CI: [1.45, 2.64] per SD)”

    Humansper SD

    A Novel Longitudinal Proteomic Aging Index Predicts Mortality, Multimorbidity, and Frailty in Older Adults

    Aging cell8 Dec 2025

CVD mortality

upin humans1HR 1.79

1 study
  1. Longitudinal proteomic aging index predicts CVD mortality in humans (HR = 1.79, 95% CI: [1.34, 2.39] per SD).

    “CVD mortality (HR = 1.79, 95% CI: [1.34, 2.39] per SD)”

    Humansper SD

    A Novel Longitudinal Proteomic Aging Index Predicts Mortality, Multimorbidity, and Frailty in Older Adults

    Aging cell8 Dec 2025

Mortality

upin humans1HR 2.5

1 study
  1. Longitudinal proteomic aging index predicts mortality in humans (HR = 2.50, 95% CI: [2.15, 2.92] per SD).

    “higher LPAI was associated with increased all-cause mortality (HR = 2.50, 95% CI: [2.15, 2.92] per SD)”

    Humansper SD

    A Novel Longitudinal Proteomic Aging Index Predicts Mortality, Multimorbidity, and Frailty in Older Adults

    Aging cell8 Dec 2025

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