Local interconnectivity of default mode and frontoparietal networks

Loneliness is associated with local interconnectivity of default mode and frontoparietal networks in humans.

“a significant interaction between loneliness and age emerged for the local interconnectivity of the Default Model and Frontoparietal networks after adjusting for key socio-demographic factors”

Humansadjusting for key socio-demographic factorsbrain

Social Disconnection in the Brain: Loneliness and Age across Networks using Graph Theory

bioRxiv : the preprint server for biology·6 Feb 2026Preprint