Liver-specific PhenoAgeAccel

Biomarker

1 paper3 findings

  • Humans1

Effects

1

Liver-related outcomes

mediatesin humans1

1 study
  1. Liver-specific PhenoAgeAccel mediates liver-related outcomes in humans (10-27%).

    “Approximately 10-27% of the associations between risk behaviors and liver-related outcomes were mediated by liver-specific PhenoAgeAccel.”

    Humansof the associations between risk behaviors and liver-related outcomes

    Liver-specific phenotypic aging, behavior and genetic risks, and long-term liver-related outcomes

    GeroScience28 Jan 2026

Associations

2

Liver-related events

upin humans1

1 study
  1. Liver-specific PhenoAgeAccel raises the risk of liver-related events in humans (1.23- to 2.97-fold increased risks).

    “Liver-specific PhenoAgeAccel was significantly associated with a 1.23- to 2.97-fold increased risks of all-cause mortality and liver-related events.”

    Humans

    Liver-specific phenotypic aging, behavior and genetic risks, and long-term liver-related outcomes

    GeroScience28 Jan 2026

Mortality

upin humans1

1 study
  1. Liver-specific PhenoAgeAccel raises the risk of mortality in humans (1.23- to 2.97-fold increased risks).

    “Liver-specific PhenoAgeAccel was significantly associated with a 1.23- to 2.97-fold increased risks of all-cause mortality and liver-related events.”

    Humans

    Liver-specific phenotypic aging, behavior and genetic risks, and long-term liver-related outcomes

    GeroScience28 Jan 2026

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 1Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 01 in 12 months