Leucine whole-body production

There is 1 paper on leucine whole-body production in aging research: 1 trial in people.

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See all 1 papers on leucine whole-body production

Human trial1

Interventions

1

Statins

downin humans1

1 study

Statins decrease leucine whole-body production in humans (hyperlipidemia) (-22%, p = 0.0033).
“We found a reduced leucine WBP (22 %, p = 0.0033), along with a reduction in valine WBP (13 %, p = 0.0224).”
Human trialhyperlipidemia7 daysn = 12
Statin treatment reduces leucine turnover, but does not affect endogenous production of beta-hydroxy-beta-methylbutyrate (HMB)
Metabolism: clinical and experimentalApr 25, 2024

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MetabolismApr 28

Statin treatment reduces leucine turnover, but does not affect endogenous production of beta-hydroxy-beta-methylbutyrate (HMB)

Non-randomized trial in 12 peopleStatins