Left ventricular collagen amount, aggregation and spatial distribution

1. Lipofuscin is associated with left ventricular collagen amount, aggregation and spatial distribution in humans (Strong correlations; coefficients not reported).

   “Remarkably, all collagen parameters strongly correlated with lipofuscin, a biological age marker, in humans.”

   Humansleft ventricle

   Analysis of age-related left ventricular collagen remodeling in living donors: Implications in arrhythmogenesis

   iScience·Jan 29, 2022

More on Lipofuscin

1. Older age is associated with left ventricular collagen amount, aggregation and spatial distribution in pigs.

   “All collagen features increased when comparing adult and old pigs with young ones”

   Animalsleft ventricle

   Analysis of age-related left ventricular collagen remodeling in living donors: Implications in arrhythmogenesis

   iScience·Jan 29, 2022