Lacunocanalicular network defect size

Age is associated with lacunocanalicular network defect size in humans.

“The size of these defects increases with age, suggesting a possible link to the concurrent reduction in bone quality.”

Humansiliac crest bonefemales

The human osteocyte lacunocanalicular network structure in osteons of the iliac crest of elderly women depends on mineral content but not individual age

Acta biomaterialia·20 Nov 2025