Jointly low telomere length and LINE-1 methylation
1 finding
Associations
1Early pregnancy loss
upin humans1OR 9.7
1 study
Early pregnancy loss
upin humans1OR 9.7
Jointly low telomere length and LINE-1 methylation is associated with early pregnancy loss in humans (OR 9.70, interval 3.94–23.72).
“significant risk of early pregnancy failure when women carried both risk conditions, low TL and LINE-1 methylation (OR = 9.70, 3.94-23.72; P < 0.0001)”
HumansBoth measures below the 25th percentile compared with both above the 75th percentilefemalesn = 242
LINE-1 Methylation sustains telomere length in pregnant women: effects on pregnancy failure
Clinical epigeneticsJul 23, 2025