Isoprene

Isoprene is associated with sweet taste sensitivity in humans.

“found several volatile compounds in the oral exhaled breath, especially the endogenous compound isoprene, that significantly correlated with oral bacteria genera and sweet taste sensitivity”

Humansoral exhaled breath

Machine learning elucidates associations between oral microbiota and the decline of sweet taste perception during aging

NPJ science of food·7 Jan 2026