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Inflammatory Resilience Index

Biomarker

1 paper studies it4 findings

1 new paper in 30 daysSee all 1

  • Humans1

Effects

1

All-cause mortality discrimination

upin humans1

1 study

  1. Inflammatory Resilience Index improves all-cause mortality discrimination in humans (ΔC-statistic +0.002).

    “Adding IRI to the base model improved discrimination for all-cause mortality (ΔC-statistic +0.002)”

    HumansAddition to the base modelMedian 13.8 yearsn = 11,854

    Resilience score linked to lower mortality in adults

    ESC Congress 2026 abstract

Associations

3

Mortality

downin humans1HR 0.71

1 study

  1. Inflammatory Resilience Index is associated with mortality in humans (29% lower mortality per 1-SD increase; HR 0.71, 95% CI 0.64–0.79).

    “each 1-SD increase in IRI was associated with 29% lower all-cause mortality (HR: 0.71; 95% CI: 0.64–0.79; P<0.001)”

    HumansWithout baseline atherosclerotic cardiovascular diseasePer 1-SD increase in IRIMedian 13.8 yearsn = 11,854

    Resilience score linked to lower mortality in adults

    ESC Congress 2026 abstract

Walking difficulty

downin humans1OR 0.69

1 study

  1. Inflammatory Resilience Index is associated with walking difficulty in humans (31% lower odds per 1-SD increase; OR 0.69, 95% CI 0.61–0.78).

    “and 31% lower odds of walking difficulty (OR: 0.69; 95% CI: 0.61–0.78; P<0.001).”

    HumansWithout baseline atherosclerotic cardiovascular diseasePer 1-SD increase in IRIn = 10,875

    Resilience score linked to lower mortality in adults

    ESC Congress 2026 abstract

Fair/poor self-reported health

downin humans1OR 0.79

1 study

  1. Inflammatory Resilience Index is associated with fair/poor self-reported health in humans (21% lower odds per 1-SD increase; OR 0.79, 95% CI 0.74–0.85).

    “each 1-SD increase in IRI was associated with 21% lower odds of fair/poor self-reported health”

    HumansWithout baseline atherosclerotic cardiovascular diseasePer 1-SD increase in IRIn = 10,875

    Resilience score linked to lower mortality in adults

    ESC Congress 2026 abstract

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 11 paper in 12 months
ESC Congress 2026 Abstract

Resilience score linked to lower mortality in adults

An observational study of 11,854 US adults followed for a median of 13.8 years linked higher scores to 29 percent lower all-cause mortality.An observational study of 11,854 US adults followed for a median of 13.8 years linked higher scores to 29 percent lower all-cause mortality.

Cohort · 11,854 peopleBiomarkers
Paper

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