Inflammatory burden index

Biomarker

1 paper2 findings

  • Humans1

Associations

2

Cardiovascular mortality

upin humans1HR 1.38

1 study
  1. Inflammatory burden index is associated with cardiovascular mortality in humans (HR 1.38, 95% CI 1.08–1.76).

    HumansDiabetes or prediabetes; highest versus lowest inflammatory burden index tertile, fully adjusted modelMedian 11.7 years of follow-upn = 8,738

    Association between inflammatory burden index and cardiovascular and all-cause mortality in individuals living with diabetes and prediabetes: a NHANES cohort study

    Integrative biology : quantitative biosciences from nano to macro16 Jan 2026

Mortality

upin humans1HR 1.42

1 study
  1. Inflammatory burden index is associated with mortality in humans (HR 1.42, 95% CI 1.24–1.63).

    HumansDiabetes or prediabetes; highest versus lowest inflammatory burden index tertile, fully adjusted modelMedian 11.7 years of follow-upn = 8,738

    Association between inflammatory burden index and cardiovascular and all-cause mortality in individuals living with diabetes and prediabetes: a NHANES cohort study

    Integrative biology : quantitative biosciences from nano to macro16 Jan 2026

Latest

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medRxiv

Inflammatory burden is linked to incident heart failure

In 6,785 adults, adjusting for four inflammatory biomarkers reduced the Black-White heart failure log-hazard difference by 57.5% relative to a clinical model.In 6,785 adults, adjusting for four inflammatory biomarkers reduced the Black-White heart failure log-hazard difference by 57.5% relative to a clinical model.

Preprint: cohort study of 6,785 peopleHeart failure