InferAging

1. InferAging is associated with intestinal barrier dysfunction in zebrafish.

   “The inferred aging state was associated with metabolic decline, intestinal barrier dysfunction, inflammation, and mucosal immune abnormalities beyond chronological age.”

   Animalsprogeroid klotho-mutant zebrafish; association beyond chronological ageintestine

   InferAging: A non-invasive aging clock for quantifying individual differences in aging

   bioRxiv (Cold Spring Harbor Laboratory)·27 May 2026Preprint

1. InferAging predicts transcriptome-integrated biological age estimates in zebrafish.

   “A non-invasive variant using behavioral and morphological snapshots reproduced the transcriptome-integrated estimates without molecular input or lifelong tracking.”

   Animalsprogeroid klotho-mutant zebrafishnon-invasive variant using behavioral and morphological snapshots

   InferAging: A non-invasive aging clock for quantifying individual differences in aging

   bioRxiv (Cold Spring Harbor Laboratory)·27 May 2026Preprint

More on Transcriptome-integrated biological age estimates

1. InferAging predicts individual biological aging states in zebrafish.

   “InferAging identified accelerated and delayed agers within the same chronological age group.”

   Animalsprogeroid klotho-mutant zebrafish

   InferAging: A non-invasive aging clock for quantifying individual differences in aging

   bioRxiv (Cold Spring Harbor Laboratory)·27 May 2026Preprint