IGH gene repertoire diversity
Biomarker1 paper1 finding
- Humans1
Upstream
1Dominant clonotype ratio greater than 10
downin humans1
1 study
Dominant clonotype ratio greater than 10
downin humans1
Dominant clonotype ratio greater than 10 decreases IGH gene repertoire diversity in humans (Beta=-0.57, p < 0.001).
Humansin a multivariable modelwhole blood30 yearsn = 98
Longitudinal analysis of the B-cell receptor repertoire across 30 years of ageing · bioRxiv · 22 Aug 2026 · Preprint