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Igf2 promoter hydroxymethylation

Biomarker

1 paper2 findings

  • Animals1

Effects

2

Long-term potentiation

upin rats1

1 study

  1. Igf2 promoter hydroxymethylation improves long-term potentiation in rats.

    “of the Igf2 promoter in the hippocampus improved memory and long-term potentiation in aged, but not middle-aged, rats.”

    AnimalsCRISPR-dCas9-mediated increase of Igf2 promoter hydroxymethylationhippocampusmales

    Increased DNA methylation of Igf2 in the male hippocampus regulates age-related deficits in synaptic plasticity and memory

    Brain research bulletin11 Aug 2025

Memory

upin rats1

1 study

  1. Igf2 promoter hydroxymethylation improves memory in rats.

    “of the Igf2 promoter in the hippocampus improved memory and long-term potentiation in aged, but not middle-aged, rats.”

    AnimalsCRISPR-dCas9-mediated increase of Igf2 promoter hydroxymethylationhippocampusmales

    Increased DNA methylation of Igf2 in the male hippocampus regulates age-related deficits in synaptic plasticity and memory

    Brain research bulletin11 Aug 2025

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