iAge

1. iAge is associated with NfL in humans (β = 0.76, 95% CI [0.23; 1.30]).

   “accelerated inflammatory aging was associated with higher NFL levels (β = 0.76, 95% CI [0.23; 1.30], p <0.01).”

   Humansaccelerated inflammatory aging in fully adjusted modelsn = 586

   Associations between epigenetic and inflammatory aging, cognitive function, and blood‐based biomarkers of Alzheimer’s disease: findings from the INSPIRE‐T cohort · AAIC 2025 abstract · 23 Dec 2025

NfL →