HCN4 membrane expression
1 paper1 finding
- Animals1
Upstream
1AMPK signalling
downin mice1
1 study
AMPK signalling
downin mice1
AMPK signalling decreases HCN4 membrane expression in mice.
“AMPK can act as a posttranslational effector by phosphorylating Ser1157 at the C terminus of HCN4, a modification associated with a decrease in HCN4 membrane expression”
Animals
AMPK-mediated HCN4 channel phosphorylation contributes to age-related intrinsic bradycardia
The Journal of general physiology6 Feb 2026
Latest
1 in 12 monthsThe Journal of General Physiology
AMPK-mediated HCN4 channel phosphorylation contributes to age-related intrinsic bradycardia
Experiments in miceAMPK signalling