Hair follicle stem cell abundance

Hair shaft miniaturization decreases hair follicle stem cell abundance.

“Persistent hair shaft miniaturization during aging and genetic hypotrichosis disorders causes long-term HFSC loss by inducing continuous ectopic apoptosis through Piezo1.”

Animalsduring aging and genetic hypotrichosis disorders; studied in vivo, species not statedhair follicle

Hair shaft miniaturization causes stem cell depletion through mechanosensory signals mediated by a Piezo1-calcium-TNF-α axis

Cell stem cell·7 Oct 2021