Circulation Research
Restoring an enzyme improved blood vessel function in aged mice
Restoring the enzyme NNMT in cells lining blood vessels improved vessel widening and reduced arterial stiffness in aged mice; lowering NNMT worsened both.Restoring the enzyme NNMT in cells lining blood vessels improved vessel widening and reduced arterial stiffness in aged mice; lowering NNMT worsened both.
Mouse studyInterventions
Who was studiedAged mice
What changedRestoring NNMT improved blood vessel widening and reduced arterial stiffness in aged mice
The catchThe experiments measured vessel widening and stiffness, not heart attacks or strokes