Growth hormone secretory burst frequency

Age decreases growth hormone secretory burst frequency in humans (r = -0.80).

“age was a major negative statistical determinant of GH secretory burst frequency (r = -0.80; P = 0.005)”

Humansmalesn = 21

Age and relative adiposity are specific negative determinants of the frequency and amplitude of growth hormone (GH) secretory bursts and the half-life of endogenous GH in healthy men

The Journal of clinical endocrinology and metabolism·1 Nov 1991