Papers on glutamate accumulation

5 papers1 new in 30 days

Monday, November 2

Frontiers in PharmacologyNov 2

Metformin regulates astrocyte autophagy via the AMPK/mTOR pathway to improve glutamate homeostasis and prevent cognitive impairment induced by cerebral ischemia-reperfusion

Accepted, not yet published: experiments in ratsMetformin

Paper

Friday, July 10

Alzheimer's & DementiaJul 10

Brain enzyme contributes to memory problems after surgery in mice

Experiments in mice aged 18–20 months implicated an enzyme in brain support cells in male-specific memory problems during the week after surgery.Experiments in mice aged 18–20 months implicated an enzyme in brain support cells in male-specific memory problems during the week after surgery.

Mouse studyMechanisms

Paper

Cell Communication and SignalingJul 10

Glutamate alters metabolism in human marrow support cells

Experiments in lab-grown human marrow support cells found signs of senescence, a state in which cells stop dividing, and increased collagen deposition after glutamate…Experiments in lab-grown human marrow support cells found signs of senescence, a state in which cells stop dividing, and increased collagen deposition after glutamate exposure.

Human cell studyAmino acid metabolism

Paper

Friday, December 29

Aging CellDec 29

Increased A1 astrocyte activation-driven hippocampal neural network abnormality mediates delirium-like behavior in aged mice undergoing cardiac surgery

Experiments in miceMechanisms

Paper

Friday, May 24

Molecular NeurobiologyMay 24

Paraquat as an Environmental Risk Factor in Parkinson's Disease Accelerates Age-Related Degeneration Via Rapid Influx of Extracellular Zn²⁺ into Nigral Dopaminergic Neurons

Experiments in animalsMechanisms

Paper