Papers on GLP-1R
146 papers13 new in 30 days
Wednesday, April 30
Friday, April 11
Trends in Pharmacological Sciences
Structural pharmacology and mechanisms of GLP-1R signaling
Wednesday, April 9
Tissue & Cell
Liraglutide attenuates high glucose-induced endothelial cell senescence and dysfunction via SIRT1-mediated deacetylation of p53/p65
Experiments in human cellsLiraglutide
Tuesday, March 18
Cell Reports Medicine
Bioengineering the metabolic network of CAR T cells with GLP-1 and Urolithin A increases persistence and long-term anti-tumor activity
Experiments in miceUrolithin A
Tuesday, February 4
Frontiers in Endocrinology
Comparative efficacy of incretin drugs on glycemic control, body weight, and blood pressure in adults with overweight or obesity and with/without type 2 diabetes: a systematic review and network meta-analysis
Meta-analysis of randomized trialsOverweight
Tuesday, December 10
Anatolian Journal of Cardiology
Acute GLP-1 Agonism Induces Arrhythmogenic Electrical Activity in Aged Mice Heart Through Impaired Cellular Na+ and Ca2+ Handlings: The Role of CK2 Hyperphosphorylation
Experiments in miceArrhythmia
Thursday, November 7
The Lancet Regional Health Europe
Why are we still in need for novel anti-obesity medications?
ReviewObesity
Tuesday, October 8
Cardiology in Review
The First Triple Agonist for Antiobesity: Retatrutide
ReviewGLP-1 receptor agonists
Friday, September 13
Molecular Metabolism
Lead-in calorie restriction enhances the weight-lowering efficacy of incretin hormone-based pharmacotherapies in mice
Experiments in miceDietary restriction
Friday, August 30
Wednesday, August 14
Friday, June 28
Diabetes, Obesity & Metabolism
Changes in lean body mass with glucagon-like peptide-1-based therapies and mitigation strategies
ReviewInterventions
Thursday, June 27
ACS Chemical Biology
Prolonged Activation of the GLP-1 Receptor via Covalent Capture
Experiments in human cellsInterventions
Wednesday, May 8
bioRxiv
Functional and multi-omic aging rejuvenation with GLP-1R agonism
Preprint: experiments in miceInterventions
Thursday, April 11
The Journal of Endocrinology
The GLP-1R as a model for understanding and exploiting biased agonism in next-generation medicines
Meta-analysis of animal and cell studiesMechanisms
Tuesday, March 5
Saturday, February 17
European Journal of Clinical Pharmacology
A review of an investigational drug retatrutide, a novel triple agonist agent for the treatment of obesity
ReviewGLP-1 receptor agonists
Monday, December 11
Basic and Clinical Neuroscience
Investigating the Glucagon-like Peptide-1 and Its Receptor in Human Brain: Distribution of Expression, Functional Implications, Age-related Changes and Species Specific Characteristics
Cross-sectional study of 30 peopleMechanisms
Friday, December 8
Friday, November 3
Frontiers in Bioscience
The Effect of Liraglutide on Lung Cancer and Its Potential Protective Effect on High Glucose-Induced Lung Senescence and Oxidative Damage
Experiments in animalsLiraglutide
Monday, August 21
Wednesday, August 16
Thursday, July 27
Thursday, June 15
Diabetes Research and Clinical Practice
Perspectives in weight control in diabetes - Survodutide
ReviewSurvodutide
Tuesday, June 6
Biochimica et Biophysica Acta Molecular Basis of Disease
Glucagon-like peptide-1 receptor agonist, semaglutide attenuates chronic liver disease-induced skeletal muscle atrophy in diabetic mice
Experiments in miceGLP-1 receptor agonists
Thursday, April 27
Tuesday, March 28
Expert Opinion on Pharmacotherapy
GLP-1/GIP analogs: potential impact in the landscape of obesity pharmacotherapy
ReviewObesity
Sunday, February 26
Expert Opinion on Pharmacotherapy
Profile of tirzepatide in the management of type 2 diabetes mellitus: design, development, and place in therapy
ReviewTirzepatide