Global histone acetylation
1 paper1 finding
- Model organisms1
Upstream
1crtc-1
mediatesin worms1
1 study
crtc-1
mediatesin worms1
crtc-1 mediates global histone acetylation in worms.
“CRTC-1 also mediates global histone acetylation levels”
Model organisms
CRTC-1 balances histone trimethylation and acetylation to promote longevity
bioRxiv (Cold Spring Harbor Laboratory)Sep 2, 2022Preprint
Latest
bioRxiv
Impact of inhibitors of histone post-translational modifications on lifespan, reproduction, and stress response in the rotifer Brachionus manjavacas
Preprint: experiments in model organismsInterventions
Nature Aging
The CRTC-1 transcriptional domain is required for COMPASS complex-mediated longevity in C. elegans
Experiments in model organismsMechanisms
bioRxiv
CRTC-1 balances histone trimethylation and acetylation to promote longevity
Preprint: experiments in wormsMechanisms
The International Journal of Neuropsychopharmacology
Early stress evokes temporally distinct consequences on the hippocampal transcriptome, anxiety and cognitive behaviour
Experiments in ratsMechanisms