Cancer Prevention Research
Eflornithine may lower a DNA damage marker in stomach lesions
Between months 18 and 24, after treatment ended, DNA damage marker scores fell 18.3 points with eflornithine versus 1.6 with placebo.Between months 18 and 24, after treatment ended, DNA damage marker scores fell 18.3 points with eflornithine versus 1.6 with placebo.
Randomized trial · 55 peopleInterventions
Who was studied55 patients with gastric premalignant conditions, 24 months, against placebo
What changedDNA damage marker scores fell more with eflornithine than placebo from 18 to 24 months: −16.7 points
The catchStomach biopsy sampling varies within patients over time, potentially affecting DNA damage measurement accuracy