GAPDH S-nitrosation
1 paper studies it2 findings
- Animals1
Effects
1Sarcopenia
upin mice1
1 study
Sarcopenia
upin mice1
GAPDH S-nitrosation increases sarcopenia in mice.
“translocation of S-nitrosated GAPDH to the nucleus and S-nitrosated GAPDH-mediated apoptosis contributed to sarcopenia.”
Animalsnatural agingskeletal muscle
GAPDH S-nitrosation contributes to age-related sarcopenia through mediating apoptosis
Nitric oxide : biology and chemistry
Upstream
1NOS2
is required forin mice1
1 study
NOS2
is required forin mice1
NOS2 is required for GAPDH S-nitrosation in mice.
“The upregulated S-nitrosation of GAPDH relies on inducible nitric oxide synthase (iNOS) rather than enzymes involved in denitrosylation.”
Animalsagingskeletal muscle
GAPDH S-nitrosation contributes to age-related sarcopenia through mediating apoptosis
Nitric oxide : biology and chemistry
Latest
Nitric Oxide
GAPDH S-nitrosation contributes to age-related sarcopenia through mediating apoptosis
Experiments in miceApoptosis