Gain of methylation at polycomb CpG islands

There is 1 paper on gain of methylation at polycomb CpG islands in aging research: none in people yet. The newest story, Nov 1, 2026: “Age-linked DNA tags varied between individual mouse cells”.

Biomarker

1 paper studies it1 more mentions it1 finding

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  • In silico1

Upstream

1

cell proliferation

upin silico1

1 study
  1. cell proliferation increases gain of methylation at polycomb CpG islands in silico.

    “faster proliferating cells showing accelerated gain of methylation”

    In silico

    Age-linked DNA tags varied between individual mouse cells

    Nature communications

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Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 1Apr 2026: 0May 2026: 0Jun 2026: 1Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 02 papers in 12 months
Nature Communications

Age-linked DNA tags varied between individual mouse cells

An analysis of 1,132 mouse white blood cells across four ages linked faster cell division to greater gains in chemical DNA tags.An analysis of 1,132 mouse white blood cells across four ages linked faster cell division to greater gains in chemical DNA tags.

Cross-sectional studyMechanisms