GABAAR-mediated currents
1 paper2 findings
- Cells1
Interventions
2Taurine
upin mice1
1 study
Taurine
upin mice1
Taurine activates GABAAR-mediated currents in mice (EC50 116 μM).
“evokes GABAAR-mediated currents with an EC50 of 0.4 μM (vs. 3.7 μM for GABA and 116 μM for taurine) in murine cerebellar granule cells”
Animalscerebellar granule cells
GABAA receptors as plausible molecular targets and mediators for taurine and homotaurine actions
Frontiers in pharmacologyDec 14, 2023
Tramiprosate
upin mice1
1 study
Tramiprosate
upin mice1
Tramiprosate activates GABAAR-mediated currents in mice (EC50 0.4 μM).
“HT is a very potent GABA mimetic, as it evokes GABAAR-mediated currents with an EC50 of 0.4 μM (vs. 3.7 μM for GABA and 116 μM for taurine)”
Animalscerebellar granule cells
GABAA receptors as plausible molecular targets and mediators for taurine and homotaurine actions
Frontiers in pharmacologyDec 14, 2023
Latest
Frontiers in Pharmacology
GABAA receptors as plausible molecular targets and mediators for taurine and homotaurine actions
Experiments in mouse cellsInterventions