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[3H]muscimol binding

Biomarker

1 paper1 finding

  • Cells1

Interventions

1

Tramiprosate

downin mice1

1 study

  1. Tramiprosate inhibits [3H]muscimol binding in mice (IC50 0.16 μM).

    “HT displaces the high affinity GABAAR ligand [3H]muscimol at similarly low concentrations (HT IC50 of 0.16 μM vs. 125 μM for taurine) in mouse brain homogenates.”

    Animalsbrain homogenates

    GABAA receptors as plausible molecular targets and mediators for taurine and homotaurine actions

    Frontiers in pharmacologyDec 14, 2023

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