Functional connectivity gradients

Biomarker1 paper1 finding

  • Humans1

Associations

1

Cognitive function

downin humans1

1 study
  1. Functional connectivity gradients are associated with cognitive function in humans.

    Humansgreater task-state left G1 range associated with lower drop error during allocentric navigationposterior cingulate cortexn = 19

    Older adults show narrower brain connectivity patterns · NeuroImage · 7 Oct 2026

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NeuroImageHumans

Older adults show narrower brain connectivity patterns

During a navigation task, one brain connectivity pattern had an approximately 65% smaller range in 19 older adults than in 19 younger adults.During a navigation task, one brain connectivity pattern had an approximately 65% smaller range in 19 older adults than in 19 younger adults.

Nature NeuroscienceHumans

Aging and Alzheimer's alter separate functional brain pathways

Two human cohorts of 973 and 129 individuals revealed that aging and Alzheimer's disease disrupt separate, orthogonal functional communication axes…Two human cohorts of 973 and 129 individuals revealed that aging and Alzheimer's disease disrupt separate, orthogonal functional communication axes across the brain.