Framingham Risk Score ≥10%

1. PANX1 predicts Framingham Risk Score ≥10% in humans (AUC 0.767, 95% CI 0.560–0.937).

   Humansnon-diabetic participants; incremental value over conventional clinical factors inconsistently establishedCD34+CD45− cells

   Pannexin 1 expression in circulating progenitor marker-positive cells is associated with senescence and cardiovascular risk

   Biomarker research·9 Oct 2026

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