Flortaucipir-PET SUVR

Biomarker

2 papers2 findings

  • Human trial1
  • Humans1

Upstream

1

Clinical Dementia Rating

upin humans1

1 study
  1. Clinical Dementia Rating increases Flortaucipir-PET SUVR in humans (25.5% vs 13.3%).

    “In the CDR0 and the CDR0.5 subgroups, 13.3% and 25.5% of participants, respectively, were tau positive (SUVR > 1.11”

    Human trialpreclinical AD with CDR-GS 0.5 vs CDR-GS 0

    Flortaucipir patterns in preclinical Alzheimer's disease: an evaluation of TRAILBLAZER‐ALZ 3 baseline data

    AAIC 2025 abstract25 Dec 2025

Associations

1

Temporal lobe

upin humans1

1 study
  1. Temporal lobe is associated with Flortaucipir-PET SUVR in humans (1.22-1.25 medial temporal vs 1.03-1.07 frontal).

    “The medial and lateral temporal lobes had the highest regional baseline SUVRs for both subgroups.”

    Human trialpreclinical AD

    Flortaucipir patterns in preclinical Alzheimer's disease: an evaluation of TRAILBLAZER‐ALZ 3 baseline data

    AAIC 2025 abstract25 Dec 2025

Latest

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